Richard J Auchus Selected Research

Prednisone (Sone)

12/2014	Use of prednisone with abiraterone acetate in metastatic castration-resistant prostate cancer.
9/2014	A-ring modified steroidal azoles retaining similar potent and slowly reversible CYP17A1 inhibition as abiraterone.
2/2012	Human steroid biosynthesis for the oncologist.

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Richard J Auchus Research Topics

Disease

30	Prostatic Neoplasms (Prostate Cancer) 01/2023 - 08/2010
29	Hypertension (High Blood Pressure) 03/2024 - 03/2003
28	Congenital Adrenal Hyperplasia (Hyperplasia, Congenital Adrenal) 11/2023 - 01/2008
23	Neoplasms (Cancer) 01/2023 - 03/2009
18	Congenital adrenal hyperplasia due to 21 hydroxylase deficiency 10/2023 - 08/2014
15	Hyperaldosteronism (Conn Syndrome) 03/2024 - 03/2003
13	Cushing Syndrome 01/2023 - 12/2007
10	Adenoma (Adenomas) 01/2021 - 03/2003
9	Virilism (Virilization) 01/2023 - 05/2006
8	Hypokalemia 03/2024 - 01/2004
7	Insulin Resistance 01/2022 - 04/2009
6	Adrenal Insufficiency (Adrenal Gland Hypofunction) 01/2024 - 02/2008
5	Isolated 17,20-Lyase Deficiency 01/2017 - 11/2002
5	Asthma (Bronchial Asthma) 05/2016 - 01/2011
4	Hyperkalemia 02/2024 - 03/2011
4	Essential Hypertension 12/2023 - 02/2008
4	Familial Hyperaldosteronism 11/2023 - 08/2012
4	Cardiovascular Diseases (Cardiovascular Disease) 10/2023 - 08/2012
4	Pituitary ACTH Hypersecretion 01/2023 - 01/2022
4	Obesity 01/2023 - 08/2014
4	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 01/2023 - 01/2011
4	Hirsutism 12/2022 - 01/2011
4	Pheochromocytoma 02/2020 - 03/2009
4	Paraganglioma (Paragangliomas) 02/2020 - 03/2009
3	Addison Disease (Addison's Disease) 02/2024 - 07/2013
3	Adrenal Gland Neoplasms (Adrenal Cancer) 01/2023 - 05/2013
3	Breast Neoplasms (Breast Cancer) 01/2023 - 02/2012
3	Type 2 Diabetes Mellitus (MODY) 01/2023 - 04/2017
3	Osteoporosis 01/2023 - 01/2021
3	Body Weight (Weight, Body) 12/2022 - 02/2007
3	Adrenal Rest Tumor 01/2022 - 06/2015
3	Lipodystrophy 01/2022 - 08/2003
3	Sexual Infantilism 01/2017 - 02/2008
3	Disorders of Sex Development (Intersexuality) 10/2012 - 01/2004
2	Dehydration (Water Stress) 02/2024 - 10/2019
2	Vomiting 02/2024 - 10/2019
2	Failure to Thrive 02/2024 - 10/2019
2	Hyperpigmentation 01/2024 - 02/2008
2	Adrenal Cortex Neoplasms (Adrenocortical Cancer) 01/2023 - 12/2011
2	Hyperplasia 12/2022 - 02/2011
2	Cardiomyopathies (Cardiomyopathy) 01/2022 - 08/2017
2	Hyperinsulinism (Hyperinsulinemia) 01/2021 - 01/2017
2	Hyperglycemia 01/2021 - 12/2014
2	Infections 01/2018 - 01/2014
2	Congenital Generalized Lipodystrophy (Berardinelli-Seip Congenital Lipodystrophy) 11/2017 - 08/2003

Drug/Important Bio-Agent (IBA)

49	AndrogensIBA 10/2023 - 01/2007
32	SteroidsIBA 11/2023 - 01/2004
31	Hydrocortisone (Cortisol)FDA LinkGeneric 02/2024 - 11/2005
18	AldosteroneIBA 03/2024 - 03/2003
16	EnzymesIBA 01/2021 - 11/2002
15	GlucocorticoidsIBA 01/2024 - 06/2010
15	Hormones (Hormone)IBA 10/2022 - 11/2005
14	Testosterone (Sustanon)FDA Link 01/2022 - 05/2006
10	Adrenocorticotropic Hormone (ACTH)FDA Link 03/2024 - 11/2005
10	abirateroneIBA 01/2023 - 02/2012
10	Steroid 17-alpha-Hydroxylase (17 alpha Hydroxylase)IBA 01/2017 - 11/2002
9	Biomarkers (Surrogate Marker)IBA 10/2023 - 01/2011
8	Androgen Receptors (Androgen Receptor)IBA 01/2021 - 12/2010
8	Oxidoreductases (Dehydrogenase)IBA 01/2020 - 01/2008
7	Abiraterone AcetateIBA 01/2023 - 02/2012
7	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2002
7	Steroid 21-Hydroxylase (21 Hydroxylase)IBA 01/2019 - 07/2013
6	ReninIBA 03/2024 - 03/2003
6	SaltsIBA 02/2024 - 03/2006
6	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 10/2015
6	Mixed Function Oxygenases (Monooxygenases)IBA 11/2017 - 11/2010
5	MineralocorticoidsIBA 11/2023 - 03/2003
5	Estrogens (Estrogen)FDA Link 01/2023 - 01/2007
5	Androstenedione (4 Androstene 3,17 dione)IBA 01/2022 - 09/2008
5	Dehydroepiandrosterone (DHEA)IBA 01/2021 - 08/2010
4	Mineralocorticoid Receptor AntagonistsIBA 03/2024 - 08/2012
4	Dexamethasone (Maxidex)FDA LinkGeneric 03/2024 - 02/2012
4	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2023 - 02/2012
4	OsilodrostatIBA 01/2023 - 01/2022
4	CytochromesIBA 01/2017 - 02/2014
3	Spironolactone (Aldactone)FDA LinkGeneric 11/2023 - 04/2009
3	Chlorthalidone (Chlortalidone)FDA LinkGeneric 11/2023 - 04/2009
3	Corticotropin-Releasing HormoneIBA 10/2023 - 07/2014
3	Cosyntropin (Cortrosyn)FDA LinkGeneric 07/2020 - 06/2014
3	PotassiumIBA 10/2019 - 01/2004
3	LigandsIBA 01/2019 - 06/2009
3	Messenger RNA (mRNA)IBA 01/2018 - 02/2011
3	ProdrugsIBA 01/2017 - 08/2014
3	Aromatase (CYP19)IBA 01/2017 - 03/2007
3	Prednisone (Sone)FDA LinkGeneric 12/2014 - 02/2012
3	Acetates (Acetic Acid Esters)FDA Link 08/2014 - 11/2011
3	Dihydrotestosterone (Androstanolone)IBA 08/2011 - 05/2006
2	Cytochrome P-450 CYP11B2 (CYP11B2)IBA 02/2024 - 10/2019
2	crinecerfontIBA 10/2023 - 01/2022
2	ChromatinIBA 01/2023 - 08/2010
2	Insulin (Novolin)FDA Link 01/2022 - 11/2017
2	17-alpha-Hydroxyprogesterone (17 Hydroxyprogesterone)IBA 02/2021 - 06/2015
2	Sulfates (Sulfates, Inorganic)IBA 01/2021 - 02/2011
2	Antihypertensive Agents (Antihypertensives)IBA 01/2021 - 01/2019
2	Mifepristone (RU 486)FDA Link 11/2018 - 01/2016
2	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 06/2017 - 11/2005

Therapy/Procedure

23	Therapeutics 02/2024 - 02/2007
22	Castration 01/2023 - 08/2010
5	Drug Therapy (Chemotherapy) 11/2021 - 04/2009
4	Adrenalectomy 03/2024 - 12/2007